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Decision making in controlling animal and zoonotic diseases

Animal diseases are caused by complex factors including infectious and non-infectious factors in many cases. In veterinary epidemiology, risk factor analysis can elucidate the factors which have strong association with the disease, which will be useful in controlling the disease effectively. Also, economic analysis helps in decision making in selecting ideal control option.

The Veterinary Epidemiology Unit is providing technical services for dairy farms in Hokkaido in disease control at community level. We also try to facilitate introduction of economics in veterinary medicine, collaborating with an EU research project.

Collaborative research: NOSAI Okhotsk

Research funding

2017-2019Establishment of preventive technology of bovine leukemia virus spread. Hokkaido Research Institute Important Research Program.
2016-2019Safe Milk Promotion in Mbarara Project. JICA Partnership Program. PI.
2014Ministry of Agriculture, Forestry, and Fisheries of Japan, Investigation into efficacy of Standard of Rearing Hygiene Management. PI.
2013-2015Epidemiological investigation into sociological impact of animal infectious disease. Technology development for rapid and effective control of important animal infectious disease. Japan Ministry of Agriculture, Forestry and Fisheries. 2013-2015. Co-PI.
2013-2015Rabies prevention policy in the disease free country. Japan Ministry of Health, Labour and Welfares, 2013-2015. Co-PI.

Performance

Peer review paper

Sasaki, Y., Toyomaki, H., Sekiguchi, S., Sueyoshi, M., Makita, K., Otake, S., Perez, A., and Alvarez. 2017. Spatial dynamics of porcine epidemic diarrhea (PED) spread in the southern Kyushu, Japan. Preventive Veterinary Medicine.

Ando T, Takino T, Makita K, Tajima M, Koiwa M, Hagiwara K. 2016. Sero-epidemiological analysis of vertical transmission relative risk of Borna disease virus infection in dairy herds. Journal of Veterinary Medical Science.

Kurosawa A, Kadowaki H, Hampson K, Makita K, et al. The rise and fall of rabies in Japan: a quantitative history of rabies epidemics in Osaka Prefecture, 1914-1933. PLOS Neglected Tropical Diseases 11(3):e0005435. doi: 10.1371/journal.pntd.0005435.

Adachi and Makita. 2017. Time series analysis based on two-part models for excessive zero count data to detect farm-level outbreaks of swine echinococcosis during meat inspections. Preventive Veterinary Medicine.

Adachi Y., Makita K. (2015) Method of time series analysis of meat inspection data using seasonal autoregressive integrated moving average model. Journal of the Japan Veterinary Medical Association 68 (3): 189-197.

Adachi Y., Makita K. (2015) Real time detection of farm-level swine mycobacteriosis outbreak using time series modelling of the number of condemned intestines in abattoirs. Journal of Veterinary Medical Science 1;77(9):1129-36.

Makita K, Tobinaga T, Kadowaki H, Yamamoto H. (2013) The effects of the types of post milking teat disinfectants on the occurrence and cost of mastitis caused by Staphylococcus aureus among dairy herds in Okhotsk, Japan. Journal of Veterinary Epidemiology 17(2): 125-131.

Makita K, Noda J, Kirisawa R. (2012) An inactivation experiment of genus Aphthovirus bovine rhinitis B virus inserted in the central part of an imported straw bale to Japan by heat and humidity treatment. J. Rakuno Gakuen Univ. 37(1), 19-23 (in Japanese).

Makita K, Fèvre EM, Waiswa C, Bronsvoort MDC, Eisler MC, Welburn SC. (2010) Population dynamics focussed rapid rural mapping and characterisation of the peri-urban interface in Kampala, Uganda, Land Use Policy, 27, 888-897.



Invited presentations

Makita K. Promotion of One Health and Ecohealth through veterinary epidemiology. Annual Conference of Japan Society of Bioinformatics. 2017 October 9, Hokkaido University, Sapporo, Japan.

Makita K. Epidemiology and its application to the field. NOSAI Hokkaido, 2017 May 17, Sapporo, Japan.

Makita K. What epidemiology can tell? From basic to application. Hokkaido Research Institute, 2017 May 17, Shintoku, Japan.

Makita K. Application of animal health economics to livestock farming. Invited speech. Japan Veterinary Association high level technical seminar, 2016 January 19, Tochigi, Japan.

Makita K. Computer simulation for rabies spread in Japan. Invited speech. Ministry of Health, Labour and Welfare, Rabies Prevention Meeting, 2016 February 23, Tokyo, Japan.

Makita K. MAFF 2014 Grant, Efficacy of Standard Rearing Hygiene Management –Porcine Epidemic Diarrhea (PED) investigation results-. Invited speech. PED Seminar, University of Miyazaki, 2016 December 8-9, Miyazaki and Kagoshima, Japan.

Makita K. (2015) Risk assessment of spread of rabies in Japan. In 15th Conference of Society of Zoonoses. National Institute of Infectious Disease, October 31, 2015.

Makita K. (2013) Evidence-based veterinary medicine and veterinary epidemiology. Japan Society for Animal Infectious Diseases.

蒔田浩平.(2011) 食品衛生モデリングの手順. 農林水産省動物医薬品検査所平成 23 年度講
演会.

蒔田浩平.(2011) オホーツク獣医師会技術講習会, フィールドで使える獣医疫学.



Presentations at international conferences

Miyama T, Watanabe E, Ogata Y, Urushiyama Y, Kawahara N, Makita K. 2017. The necessity of controlling bovine leptospirosis in Japan. OIE Joint Collaborating Centre for Food Safety Seminar, 2017 January 16th, Rakuno Gakuen University, Ebetsu, Japan.

Makita K, Yamamoto T. 2016. Comparative analysis of inter-farm spread of porcine epidemic diarrhea in Miyazaki and Kagoshima Prefectures in Japan using mathematical modeling. Japan-Republic of Korea Joint Symposium on Veterinary Epidemiology, 2016 June 11, University of Tokyo, Tokyo, Japan.

Makita K., Toyomaki H., Sekiguchi S., Sasaki Y., Sueyosh M. (2015) Factors associated with inter-farm spread of porcine epidemic diarrhea (PED) in Kagoshima and Miyazaki Prefectures, Japan. International Society for Veterinary Epidemiology and Economics (ISVEE 14) conference, poster presentation, November 2015, Merida, Mexico.

Kadowaki H., Makita K., Hampson K., Yamada A. (2015) Assessment of current rabies prevention act in Japan using infectious disease modelling. International Society for Veterinary Epidemiology and Economics (ISVEE 14) conference, oral presentation, Merida, Mexico, November 6, 2015.

Maita K., Yokozawa T., Uraguchi K., Makita K. (2015) Developing a method estimating red fox population from feces count in Nemuro Peninsular, Japan.5th International Wildlife Management Congress, oral presentation, Sapporo, Japan, July, 2015.

Makita K., Toyomaki H., Sekiguchi S., Sasaki Y., Sueyosh M. (2015) Spatio-temporal analysis of porcine epidemic diarrhea (PED) epidemic in Kagoshima and Miyazaki, Japan in 2014.7th International Symposium on Emerging and Re-emerging Pig Diseases. Oral presentation, June 2015, Kyoto, Japan.

Toyomaki H., Sekiguchi S., Sasaki Y., Sueyosh M., Makita K. (2015) Effective farm level biosecurity measures against porcine epidemic diarrhea (PED) epidemic in Kagoshima and Miyazaki, Japan.7th International Symposium on Emerging and Re-emerging Pig Diseases. Poster presentation, June 2015, Kyoto, Japan.



Presentations at conferences in Japan

Fujimoto Y, Nakada S, Ito H, Makita K. 2017. Association between farm hygiene management and productivity of daily cattle. SaSSOH, 2017 September 21, Hokkaido University.

Miyama T, Murata R, Okamura I, Byaruhanga J, Mwebembezi W, Muramatsu Y, Makita K. 2017. Prevalence of mastitis and dairy hygiene in dairy farms in Mbarara District, Uganda. Japan Society of Veterinary Medical Science. 2017 September 14, Kagoshima University.

Fujimoto Y, Ito H, Higuchi T, Makita K, Ohno H. 2017. Epidemiological investigation of Mycoplasma mastitis in Nemuro. Japan Society of Veterinary Medical Science. 2017 September 14, Kagoshima University.

Fukae M, Ohnishi A, Kurosawa T, Fujishiro R, Yokoyama S, Ohno H, Yamagata A, Adachi M. 2017. Principal component analysis of the farm level factors associated with pork meat inspection results. Japanese Society of Veterinary Public Health. 2017 September 7, Hokkaido University.

Karasawa M, Uraguchi K, Hayama Y, Makita K. 2017. Multivariable spatio-temporal analysis of ecological factors associated with fox feces count in Nemuro, Hokkaido. Japan Society of Veterinary Epidemiology. 2017 March 25, University of Tokyo.

Miyama T, Toyomaki H, Sekiguchi S, Sasaki Y, Sueyoshi M, Makita K. 2017. Effect of feedback immunization in PED infected farms in Kagoshima and Miyazaki Prefectures. Japan Society of Veterinary Epidemiology. 2017 March 25, University of Tokyo.

Miyama T, Watanabe E, Ogata Y, Urushiyama Y, Kawara N, Makita K. 2017. Farm level risk factor for Leptospira Hardjoindairy herds in Yamagata Prefecture. 54th Leptospira symposium. 2017 March 22, Sendai, Japan.

Nakata S, Makita K, et al. 2016. Statistical model for estimating bovine leukaemia virus load in blood. Hokkaido Veterinary Association Conference, 2016 Sep 1-2, Asahikawa, Japan.

Miyama T, Makita K, et al. 2016. Evaluation of prevention measures for bovine leukaemia virus new infections in the infected farms. Hokkaido Veterinary Association Conference, 2016 Sep 1-2, Asahikawa, Japan.

Ito H, Higuchi H, Makita K. 2016. Epidemiological investigation for Mycoplasma mastitis occurrence in Nemuro, Japan. Japan Society for Veterinary Medical Science, September 6-8, Nihon University, Kanagawa, Japan.

Nakata S, Makita K. 2016. A case-control study for bovine salmonellosis in Nemuro, Japan. Japan Society for Veterinary Medical Science, September 6-8, Nihon University, Kanagawa, Japan.

Ito H, Higuchi H, Makita K. 2016. Descriptive epidemiology of the incidence of Mycoplasma mastitis in Nemuro, Japan. Japan Society for Veterinary Epidemiology, 2016 March 20, University of Tokyo, Tokyo, Japan.

Makita K, Yamamoto T. 2016. Analysis of inter-farm spread of porcine epidemic diarrhea using mathematical modeling. Japan Society for Veterinary Epidemiology, 2016 March 20, University of Tokyo, Tokyo, Japan.

Kadowaki H., Makita K., Hampson K., Yamada A. (2015) Prediction of spread of rabies at its invasion into Japan. Japan Society of Veterinary Medical Science.

Makita K., Toyomaki H., Sekiguchi S., Sasaki Y., Sueyosh M. (2015) Spatio-temporal analysis of spread of porcine epidemic diarrhea (PED) in Kagoshima and Miyazaki Prefectures, Japan. Japan Society for Veterinary Epidemiology Conference.

Makita K., Niemi JK., Waret-Szkuta A., Gethmann J., Aragrande M., Hogeveen H., Hasler B., Bennani H., Rushton J. (2015) NEAT: Networking to enhance the use of economics in animal health education, policy making and research in Europe and beyond. Japan Society for Veterinary Epidemiology Conference.

Koide K., Murata R., Khoa AX., Ly NK., Tam PT., Tra VTT., Nhiem DV., Kono H., Makita K. (2015) Causes of mastitis and repeat-breeding of dairy herds in a select dairy production area of Vietnam. Japan Society for Veterinary Epidemiology Conference.

Yokozawa T, Uraguchi K, Makita K. (2014) Estimation of fox population and environmental parameters in Nemuro Peninsura, Hokkaio. Conference of Japan Society of Veteirnary Epidemiology.

Kurosawa A, Tojinbara K, Makita K. (2014) Epidemiological analysis of rabies epidemics in Osaka, Japan between 1910s and 1930s. Conference of Japan Society for Veterinary Epidemiology.

Tobinaga T, Yamamoto H, Makita K. (2011) Factors associated with staphylococcal mastitis in dairy herds. Conference of Japan Society for Veterinary Epidemiology.

Rakuno Gakuen University Veterinary Epidemiology(2014.05.16)|
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